Liver Metastasis

Transarterial Embolization for Liver Metastasis from Breast Cancer

Clinical Background

A 43-year-old female, originally diagnosed with breast cancer, underwent mastectomy followed by multiple systemic chemotherapy regimens. Two years later, she received a transarterial chemoembolization (TACE) procedure.

Five years from diagnosis, imaging identified a new, solitary, unresectable metastatic lesion in Segment V of the liver. The patient was referred for embolization as a liver-directed therapy.

Baseline MRI

Pre-HES Embolization Angiogram

Tumor Characteristics

  • Location: Segment V, liver
  • Lesion Type: Solitary metastasis from breast cancer
  • Vessel Diameter: 1.1 mm

Post-HES Embolization Angiogram

Intervention Details

  • Approach: Transarterial embolization with Embrace HES via transradial access
  • Embrace HES Volume: 0.4 mL delivered
  • Procedure Outcome: Successful embolization achieved

30 Day Follow-Up MRI

30-Day Follow-up

  • Core Lab reported Stable Disease (RECIST 1.1), 28% reduction in diameter
  • No local tumor progression
  • No revascularization

90 Day Follow-Up MRI

90-Day Follow-up

  • Core Lab reported Partial Response (RECIST 1.1), 45% reduction in diameter
  • No local tumor progression
  • No revascularization

Conclusion

This case demonstrates the role of transarterial embolization with Embrace HES in managing unresectable liver metastases from breast cancer. Treatment of the solitary Segment V lesion achieved sustained tumor control, with no contrast uptake or local progression through 90 days, and partial response by mRECIST criteria.

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